BriMindInvest Logo

Amgen Inc. (AMGN) Stock Analysis 2026

BiotechnologyLarge-Cap Biotechnology
$378.87as of 2026-08-03

BriMind AI Score

Proprietary
48
Neutral
Price CAGR
11.3%
1Y Return
+29.7%
Analyst Upside
-7.3%
Rev Growth
5.8%

Score based on historical price CAGR, revenue growth, analyst upside, and valuation factors. Updated daily.

BriMind 1-Year Price Target

$450.71+19.0% potential
Bear Case
$295.75
Bull Case
$551.40
Model Confidence90%

BriMind AI combines DCF, momentum, and analyst consensus to project a 12-month price target.

AI scores and price targets are for informational and educational purposes only. They do not constitute financial advice or a recommendation to buy or sell any security. Past performance is not indicative of future results. Always conduct your own research before making investment decisions. Full Disclaimer →

About Amgen Inc.

Amgen is one of the world's largest biotechnology companies, focused on developing therapies in oncology, cardiovascular, bone health, inflammation, and neuroscience. The company's blockbuster drugs include Repatha (cholesterol), Prolia/Xgeva (bone), Enbrel (inflammation), and the obesity drug MariTide (in development). Amgen's $27.8B acquisition of Horizon Therapeutics (2023) added rare disease therapies including Tepezza (thyroid eye disease). Amgen's obesity pipeline (MariTide) has made it a dark horse in the GLP-1 weight loss race.

How Amgen Makes Money

Amgen discovers, develops, manufactures, and sells biologic therapies. Revenue comes from established brands (~60% — Enbrel, Prolia, Xgeva, Otezla), growth brands (~25% — Repatha, Tezspire, Evenity, Lumakras), and Horizon products (~15% — Tepezza, Krystexxa, Uplizna). The company has a large biosimilar business providing additional revenue. Amgen's manufacturing expertise in biologics (protein-based drugs) is a core competitive advantage.

Amgen Revenue & Profitability Breakdown

This chart shows how Amgen's revenue flows through to profit. Each row deducts a layer of costs: first the direct cost of making products/services (Cost of Revenue), then operating expenses like marketing and R&D, then taxes. What remains at the bottom is net income — the actual profit shareholders own. High gross and net margins indicate a business with strong pricing power and efficiency.

Revenue
$37.22B
Cost of Revenue
-$10.63B
Gross Profit
$26.59B71.4% margin
Operating Expenses
-$14.01B
Operating Income
$12.58B33.8% margin
Tax & Other
-$4.78B
Net Income
$7.80B21.0% margin
Gross Margin
71.4%
Operating Margin
33.8%
Net Margin
21.0%
EBITDA Margin
46.1%

Key Financial Metrics

A snapshot of the company's valuation, growth, profitability, and financial health. Key things to look at: P/E ratio measures how much you pay for $1 of earnings (lower = cheaper, but fast-growing companies command higher P/E); Free Cash Flow is the cash left after running the business — companies with strong FCF can buy back shares, pay dividends, or invest; Debt/Equity shows how leveraged the company is (high debt can be risky); Return on Equity tells you how efficiently the company generates profit from shareholders' money.

Market Cap
$207.87B
Enterprise Value
$204.68B
P/E (Trailing)
26.80
P/E (Forward)
16.43
EV / EBITDA
13.02
Price / Sales
4.57
Price / Book
25.15
Revenue
$37.22B
Revenue Growth
5.8%
Earnings Growth
4.4%
EBITDA
$15.73B
Gross Margin
71.4%
Operating Margin
33.8%
Net Margin
21.0%
Return on Equity
101.3%
Return on Assets
8.3%
Free Cash Flow
$7.44B
Total Cash
$8.81B
Total Debt
$57.38B
Debt / Equity
623.75
Current Ratio
1.26
Quick Ratio
0.85
Beta
0.40
Dividend Yield
2.6%
Payout Ratio
67.2%
Book Value / Share
$17.03

Wall Street Analyst Consensus

Professional analysts at investment banks set 12-month price targets after researching the company's earnings, competitive position, and industry trends. Strong Buy / Buy means the majority expect meaningful upside. Hold means analysts see fair value near the current price — not a sell signal, but limited near-term upside expected. The mean target is the average of all analyst price targets; the range shows where the most optimistic and most cautious analysts stand.

Consensus RatingHold(28 analysts)
SellStrong Buy
Low Target$185.00-51.2%
Mean Target$357.03-5.8% upside
High Target$400.00+5.6%

Intrinsic Value Estimates for AMGN

Intrinsic value is what a stock is truly worth based on the company's fundamentals — independent of what the market currently prices it at. We use multiple models because no single formula is perfect: each captures different aspects of a business. If multiple models agree the stock is undervalued, that convergence is a stronger signal. A stock trading well below its intrinsic value may be a bargain; one far above may carry more risk.

DCF Model (10yr)
$290.44
-23.3% vs current
Discounts 10 years of projected free cash flow back to today's dollars (5% growth, 10% discount rate). Best for companies generating consistent cash.
Fair Value Range
$290.44 – $290.44
Average Estimate
$290.44
Potential Downside
-23.3%

⚠️ Intrinsic value estimates use simplified models (Graham, DCF, P/E) and conservative assumptions. They should be used as one input among many — not as sole buy/sell guidance. For advanced analysis, see the full platform.

AMGN Investment Case: Bull vs Bear

Every investment has two sides. The bull case outlines the key reasons the stock could outperform — competitive advantages, growth catalysts, and market tailwinds. The bear case highlights the most significant risks that could cause the investment to underperform. Good investors read both sides carefully before deciding. A strong bull case with manageable bear risks typically makes for a more compelling investment.

Bull Case (Reasons to Buy)

  • MariTide obesity drug uses a novel monthly injection approach — if successful in Phase 3, it could compete in the $100B+ GLP-1 market against Lilly and Novo Nordisk.
  • Horizon acquisition adds high-growth rare disease portfolio — Tepezza alone has $2B+ peak sales potential with minimal competition.
  • Repatha (PCSK9 cholesterol drug) is accelerating as guidelines expand to recommend earlier use and payers improve coverage.
  • Biosimilar portfolio provides steady revenue and cash flow as branded biologic patents expire across the industry.

Bear Case (Key Risks)

  • Enbrel erosion continues as biosimilar competition intensifies — Enbrel was once a $5B+ drug and continues to decline.
  • MariTide clinical data is still early — Phase 2 results were promising but Phase 3 failure would remove the obesity premium from the stock.
  • $27.8B Horizon acquisition added significant debt — Amgen's balance sheet is more leveraged than historically typical.
  • Patent expirations across multiple products (Otezla, Prolia) require constant pipeline replenishment.

What to Watch: AMGN Key Metrics

MariTide Phase 3 clinical data
Horizon product revenue growth
Repatha volume and revenue growth
Enbrel erosion rate
Free cash flow and debt reduction

AMGN Stock — Frequently Asked Questions

Compare AMGN with Peers

AMGN vs LLYAmgen vs Eli Lilly — Diversified Biotech vs Obesity Lea
AMGN vs ABBVAmgen vs AbbVie — Which Biotech/Pharma Dividend Stock W
ABBV vs AMGNAbbVie vs Amgen — Which Biotech Dividend Giant Wins?
AMGN vs GILDAmgen vs Gilead Sciences — Which Established Biotech Is
AMGN vs BIIBAmgen vs Biogen — Which Established Biotech Wins?
AMGN vs REGNAmgen vs Regeneron — Two Biotechnology Giants Compared

AMGN — Related Investment Themes

Top GLP-1 & Obesity Drug Stocks8 stocks in themeTop Biomedical & Pharma Stocks10 stocks in theme

Unlock the Full AMGN Analysis

Interactive price charts, real-time AI signals, advanced DCF models, portfolio tracking, earnings analysis, and side-by-side peer comparisons. Start your 14-day free trial — no credit card required.

Start Free TrialBrowse All Stocks
← Back to Home · Browse All Stock Analysis