Oruka Therapeutics, Inc. (ORKA) Stock Analysis 2026

HealthcareBiotechnology

BriMind AI Score

Proprietary
25
Weak
Price CAGR
-15.1%
1Y Return
+243.8%
Analyst Upside
+61.3%

Score based on historical price CAGR, revenue growth, analyst upside, and valuation factors. Updated daily.

AI scores and price targets are for informational and educational purposes only. They do not constitute financial advice or a recommendation to buy or sell any security. Past performance is not indicative of future results. Always conduct your own research before making investment decisions. Full Disclaimer →

Key Financial Metrics

Oruka Therapeutics, Inc. doesn't carry a meaningful trailing P/E right now, generates $-65.0M in free cash flow, runs a debt/equity ratio of 0.23, and converts shareholder equity into profit at a -18.2% return on equity. For context: P/E ratio measures how much you pay for $1 of earnings (lower = cheaper, but fast-growing companies command higher P/E); Free Cash Flow is the cash left after running the business; Debt/Equity shows how leveraged a company is; Return on Equity shows how efficiently it turns shareholder capital into profit.

Market Cap
$6.07B
P/E (Forward)
-32.34
Price / Book
5.03
EPS (Trailing)
$-2.04
EPS (Forward)
$-2.83
Gross Margin
0.0%
Operating Margin
0.0%
Net Margin
0.0%
Return on Equity
-18.2%
Return on Assets
-13.0%
Free Cash Flow
$-65.0M
Debt / Equity
0.23
Current Ratio
38.51
Quick Ratio
38.03
Beta
-0.16
Dividend Yield
None
Payout Ratio
0.0%
Insider Ownership
1.3%
Inst. Ownership
116.5%
Short % Float
18.3%
Book Value / Share
$18.20

Wall Street Analyst Consensus

Wall Street analysts covering Oruka Therapeutics, Inc. currently haven't converged on a clear consensus rating, with a mean 12-month price target of $155.00. Analysts set these targets after researching a company's earnings, competitive position, and industry trends — Strong Buy / Buy means the majority expect meaningful upside, while Hold means fair value near the current price rather than a sell signal.

Mean Target$155.00

Technical Price Signals

ORKA is currently in a mixed technical position. Moving averages smooth out day-to-day volatility to reveal the underlying trend — a Golden Cross (50MA crosses above 200MA) is a classic bullish signal, a Death Cross is bearish, though both are lagging indicators that confirm trends rather than predict them.

50-Day MA
$94.88
200-Day MA
$57.23

Further Reading

Research and guides that put ORKA’s numbers in context — how to read the filings behind them, and the frameworks we use to score them.

Market TheoryStock Market Seasonality: Monthly Returns, 'Sell in May,' and What History SaysMarket TheoryWe Backtested 929 Insider Cluster Buys — The Signal Everyone Trusts Loses to the S&P 500Fundamentals58% of Insider Selling Is Noise — How to Find the Part That MattersMarket TheoryThe Stock-Split Pop Is a Myth: What 39 Real Splits Actually Did

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Data sources: Financial metrics and market data sourced from company SEC filings, earnings releases, and investor relations disclosures. Price data, analyst consensus targets, and fundamental financials provided by financial market data providers. ETF data sourced from official fund prospectuses and index provider publications. AI scores and price targets are proprietary estimates — see our Methodology and Disclaimer for details.
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