Twist Bioscience Corporation (TWST) Stock Analysis 2026

HealthcareBiotechnology

BriMind AI Score

Proprietary
61
Moderate
Price CAGR
33.4%
1Y Return
+310.2%
Analyst Upside
+20.2%
Rev Growth
23.2%

Score based on historical price CAGR, revenue growth, analyst upside, and valuation factors. Updated daily.

AI scores and price targets are for informational and educational purposes only. They do not constitute financial advice or a recommendation to buy or sell any security. Past performance is not indicative of future results. Always conduct your own research before making investment decisions. Full Disclaimer →

TWST Revenue & Profitability Breakdown

This chart shows how TWST's revenue flows through to profit. Each row deducts a layer of costs: first the direct cost of making products/services (Cost of Revenue), then operating expenses like marketing and R&D, then taxes. What remains at the bottom is net income — the actual profit shareholders own. High gross and net margins indicate a business with strong pricing power and efficiency.

Revenue
$431.8M
Cost of Revenue
-$207.4M
Gross Profit
$224.4M52.0% margin
Operating Expenses
-$224.4M
Operating Income
$0-30.6% margin
Tax & Other
-$136.7M
Net Income
-$-136.7M-31.7% margin
Gross Margin
52.0%
Operating Margin
-30.6%
Net Margin
-31.7%

Key Financial Metrics

Twist Bioscience Corporation doesn't carry a meaningful trailing P/E right now, generates $-64.8M in free cash flow, runs a debt/equity ratio of 24.36, and converts shareholder equity into profit at a -29.6% return on equity. For context: P/E ratio measures how much you pay for $1 of earnings (lower = cheaper, but fast-growing companies command higher P/E); Free Cash Flow is the cash left after running the business; Debt/Equity shows how leveraged a company is; Return on Equity shows how efficiently it turns shareholder capital into profit.

Market Cap
$8.21B
P/E (Forward)
-206.84
Price / Book
18.42
Revenue
$431.8M
Revenue Growth
23.2%
EPS (Trailing)
$-2.23
EPS (Forward)
$-0.63
Gross Margin
52.0%
Operating Margin
-30.6%
Net Margin
-31.7%
Return on Equity
-29.6%
Return on Assets
-13.1%
Free Cash Flow
$-64.8M
Debt / Equity
24.36
Current Ratio
2.67
Quick Ratio
1.98
Beta
2.16
Dividend Yield
None
Payout Ratio
0.0%
Insider Ownership
1.0%
Inst. Ownership
118.5%
Short % Float
28.8%
Book Value / Share
$7.11

Wall Street Analyst Consensus

Wall Street analysts covering Twist Bioscience Corporation currently haven't converged on a clear consensus rating, with a mean 12-month price target of $105.30. Analysts set these targets after researching a company's earnings, competitive position, and industry trends — Strong Buy / Buy means the majority expect meaningful upside, while Hold means fair value near the current price rather than a sell signal.

Mean Target$105.30

Technical Price Signals

TWST is currently in a mixed technical position. Moving averages smooth out day-to-day volatility to reveal the underlying trend — a Golden Cross (50MA crosses above 200MA) is a classic bullish signal, a Death Cross is bearish, though both are lagging indicators that confirm trends rather than predict them.

50-Day MA
$108.69
200-Day MA
$63.25

Further Reading

Research and guides that put TWST’s numbers in context — how to read the filings behind them, and the frameworks we use to score them.

Market TheoryThe Stock-Split Pop Is a Myth: What 39 Real Splits Actually DidMarket Theory10-Year Treasury Yield Hits 19-Year High: What 5.2% Means for StocksRisk ManagementBest ETFs for a Recession-Proof Portfolio in 2026FundamentalsHow to Read a 10-K Annual Report: Complete Investor Guide

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Data sources: Financial metrics and market data sourced from company SEC filings, earnings releases, and investor relations disclosures. Price data, analyst consensus targets, and fundamental financials provided by financial market data providers. ETF data sourced from official fund prospectuses and index provider publications. AI scores and price targets are proprietary estimates — see our Methodology and Disclaimer for details.
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