Summit Therapeutics Inc. (SMMT) Stock Analysis 2026

HealthcareBiotechnology
$16.20
as of 2026-10-29
-7.3% (52-week)50D MA $14.08  |  200D MA $16.43

BriMind AI Score

Proprietary
31
Weak
Price CAGR
2.1%
1Y Return
-19.8%
Analyst Upside
+83.5%

Score based on historical price CAGR, revenue growth, analyst upside, and valuation factors. Updated daily.

BriMind 1-Year Price Target

$22.15+36.7% potential
Bear Case
$9.82
Bull Case
$32.85
Model Confidence90%

An even blend of the BriMind AI model's DCF and momentum target ($14.06) and Wall Street's consensus target ($30.24).

AI scores and price targets are for informational and educational purposes only. They do not constitute financial advice or a recommendation to buy or sell any security. Past performance is not indicative of future results. Always conduct your own research before making investment decisions. Full Disclaimer →

Key Financial Metrics

Summit Therapeutics Inc. doesn't carry a meaningful trailing P/E right now, generates $-139.7M in free cash flow, runs a debt/equity ratio of 3.24, and converts shareholder equity into profit at a -192.5% return on equity. For context: P/E ratio measures how much you pay for $1 of earnings (lower = cheaper, but fast-growing companies command higher P/E); Free Cash Flow is the cash left after running the business; Debt/Equity shows how leveraged a company is; Return on Equity shows how efficiently it turns shareholder capital into profit.

Market Cap
$11.65B
P/E (Forward)
-12.20
Price / Book
18.39
EPS (Trailing)
$-1.11
EPS (Forward)
$-1.20
Gross Margin
0.0%
Operating Margin
0.0%
Net Margin
0.0%
Return on Equity
-192.5%
Return on Assets
-101.6%
Free Cash Flow
$-139.7M
Debt / Equity
3.24
Current Ratio
6.96
Quick Ratio
6.67
Beta
-1.24
Dividend Yield
None
Payout Ratio
0.0%
Insider Ownership
80.9%
Inst. Ownership
17.4%
Short % Float
23.9%
Book Value / Share
$0.79

Wall Street Analyst Consensus

Wall Street analysts covering Summit Therapeutics Inc. currently haven't converged on a clear consensus rating, with a mean 12-month price target of $28.38 (+75.2% vs the current price). Analysts set these targets after researching a company's earnings, competitive position, and industry trends — Strong Buy / Buy means the majority expect meaningful upside, while Hold means fair value near the current price rather than a sell signal.

Mean Target$28.38+75.2% upside

Technical Price Signals

SMMT is currently in a short-term uptrend, trading above its 50-day average of $14.08 and below its 200-day average of $16.43. Moving averages smooth out day-to-day volatility to reveal the underlying trend — a Golden Cross (50MA crosses above 200MA) is a classic bullish signal, a Death Cross is bearish, though both are lagging indicators that confirm trends rather than predict them.

Current Price
$16.20
50-Day MA
$14.08
▲ Price above
200-Day MA
$16.43
▼ Price below
Short-term Uptrend
Above 50-day MA but mixed longer-term

Compare SMMT with Peers

SRPT vs SMMTSarepta Therapeutics vs Summit Therapeutics — Rare Dise

Further Reading

Research and guides that put SMMT’s numbers in context — how to read the filings behind them, and the frameworks we use to score them.

FundamentalsFactor Investing Guide 2026: Value, Momentum, Quality & Low Volatility — Which Factors Work?Risk ManagementHow to Build Your First Investment Portfolio: Risk Tolerance, Asset Allocation & Your First 5 FundsFundamentalsWarren Buffett Retired 2026: Berkshire Portfolio Under Greg AbelBeginnerWhat Is an AI Stock Score? How BriMindInvest Ranks Stocks

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Data sources: Financial metrics and market data sourced from company SEC filings, earnings releases, and investor relations disclosures. Price data, analyst consensus targets, and fundamental financials provided by financial market data providers. ETF data sourced from official fund prospectuses and index provider publications. AI scores and price targets are proprietary estimates — see our Methodology and Disclaimer for details.
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