LLY vs JNJ Comparison: AI Score, Valuation, Performance and Upside
Compare Eli Lilly's Zepbound/Mounjaro-driven growth against Johnson & Johnson's broader, more diversified pharmaceutical and medtech portfolio.
Use this Eli Lilly vs Johnson & Johnson comparison to evaluate the key differences across valuation, growth, profitability, and risk before making an investment decision.
LLY holds the edge across 4 of 5 key metrics in this comparison. LLY has delivered stronger 1-year price return (+51.85% vs +50.62%), though JNJ has the better forward P/E setup (21.78x vs 24.87x for LLY). LLY leads on both revenue growth (47.70%) and operating margin (54.22%), suggesting a stronger fundamental setup on both dimensions. Analyst consensus implies meaningfully more upside for LLY (+11.96%) than for JNJ (+1.66%).
Human Wall Street analysts' price targets, typically implying a ~12-month view — a separate signal from this site's own AI Prediction Signal further down the page, which is a 5-/30-day machine-learning forecast based on price history alone.
| Metric | LLY | JNJ |
|---|---|---|
| AI scorei | 75.8 | 49.9 |
| AI ranki | #21 | #553 |
| Latest closei | $1,136.11 | $267.20 |
| 1M returni | -3.73% | +2.63% |
| 6M returni | +22.12% | +12.22% |
| 1Y returni | +51.85% | +50.62% |
How much would $10,000 be worth today if invested at the start of each period, with all dividends reinvested?
| Period | LLY | JNJ |
|---|---|---|
| 1Y ago | $14.86K (+48.6%) started 2025-09-16 | $15.14K (+51.4%) started 2025-09-16 |
| 5Y ago | $53.18K (+431.8%) started 2021-09-17 | $19.96K (+99.6%) started 2021-09-17 |
| 10Y ago | $195.12K (+1851.2%) started 2016-09-19 | $37.29K (+272.9%) started 2016-09-19 |
Hypothetical — past performance does not guarantee future results.
| Metric | LLY | JNJ |
|---|---|---|
| Market capi | $1.05T | $645.95B |
| Trailing P/Ei | 39.36 | 31.06 |
| Forward P/Ei | 24.87 | 21.78 |
| Price/Salesi | 14.10 | 4.18 |
| EV/Revenuei | 13.72 | 6.88 |
| Analyst targeti | $1,315.04 | $272.50 |
| Target upsidei | +11.96% | +1.66% |
| Metric | LLY | JNJ |
|---|---|---|
| Revenue growthi | 47.70% | 6.60% |
| Earnings growthi | 26.20% | -0.90% |
| EPS growthi | +26.20% | -0.90% |
| FCF margini | +13.89% | +17.24% |
| Operating margini | 54.22% | 29.19% |
| Profit margini | 33.53% | 21.48% |
| ROIC proxyi | 102.29% | 25.74% |
| Return on equityi | 102.29% | 25.74% |
| Dividend yieldi | 0.59% | 2.00% |
| Payout ratioi | 21.69% | 60.79% |
| Dividend growth streaki | No increase yet | No increase yet |
| Betai | 0.51 | 0.23 |
| Debt/equityi | 162.07 | 57.71 |
| Current ratioi | 1.35 | 1.09 |
| Quick ratioi | 0.68 | 0.72 |
Over the past year, LLY and JNJ have moved moderately in the same direction (correlation of 0.43), based on daily returns.
Lower drawdown and smaller single-period drops generally indicate a smoother ride, though they do not guarantee lower future risk.
| Period | Metric | LLY | JNJ |
|---|---|---|---|
| 1Y | Growthi | +48.57% | +51.42% |
| CAGRi | +48.68% | +51.55% | |
| Volatilityi | 35.77% | 19.11% | |
| Sharpe ratioi | 1.16 | 2.04 | |
| Sortino ratioi | 1.96 | 3.24 | |
| Max drawdowni | 23.31% | 10.96% | |
| Current drawdowni | 11.26% | 4.03% | |
| Avg drawdowni | 6.51% | 2.94% | |
| Ulcer Indexi | 8.56% | 4.12% | |
| Max daily dropi | 7.79% | 3.66% | |
| Max wkly dropi | 8.60% | 6.22% | |
| 5Y | Growthi | +412.31% | +79.51% |
| CAGRi | +38.67% | +12.42% | |
| Volatilityi | 32.75% | 17.61% | |
| Sharpe ratioi | 1.03 | 0.50 | |
| Sortino ratioi | 1.59 | 0.74 | |
| Max drawdowni | 34.48% | 18.41% | |
| Current drawdowni | 11.26% | 4.03% | |
| Avg drawdowni | 7.38% | 7.01% | |
| Ulcer Indexi | 10.20% | 8.57% | |
| Max daily dropi | 14.14% | 7.59% | |
| Max wkly dropi | 17.93% | 9.18% | |
| 10Y | Growthi | +1564.19% | +186.90% |
| CAGRi | +32.50% | +11.13% | |
| Volatilityi | 30.55% | 18.84% | |
| Sharpe ratioi | 0.93 | 0.42 | |
| Sortino ratioi | 1.44 | 0.59 | |
| Max drawdowni | 34.48% | 27.37% | |
| Current drawdowni | 11.26% | 4.03% | |
| Avg drawdowni | 6.95% | 6.41% | |
| Ulcer Indexi | 9.34% | 7.97% | |
| Max daily dropi | 14.14% | 10.04% | |
| Max wkly dropi | 17.93% | 13.25% |
| Category | LLY | JNJ |
|---|---|---|
| Company | LLY | JNJ |
| Sector | Healthcare | Healthcare |
| Industry | Drug Manufacturers - General | Drug Manufacturers - General |
| Core business | Eli Lilly and Company discovers, develops, manufactures, and markets human pharmaceutical products in the United States, Europe, China, Japan, and internationally. | Johnson & Johnson, together with its subsidiaries, engages in the research and development, manufacture, and sale of a range of products in the healthcare field worldwide. |
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