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STE
STERIS plc · Health Care - Medical Equipment & Services
$202.61
-5.51% this month
VERSUS
COMPARE
DHR
Danaher Corporation · Health Care - Life Sciences & Diagnostics
$177.17
+6.06% this month
Scoreboard verdict
Across AI score, momentum, valuation, upside, operating margin
STE
1
DHR
4
DHR LEADS 4/5
Comparison scoreboard
DHR LEADS 4/5
AI Score
STE 49.9
DHR 50.3
1Y Return
STE -14.54%
DHR -9.49%
Fwd P/E
STE 17.14
DHR 19.47
Target Up.
STE +23.75%
DHR +34.56%
Op. Margin
STE 20.04%
DHR 22.94%
Metrics last refreshed: 6/20/2026
Quick take

STE vs DHR Stock Comparison: AI Score, Valuation, Performance and Upside

STE (STERIS) is a specialized sterilization and surgical services company with durable recurring revenue from hospital contracts, while DHR (Danaher) is a diversified life science and diagnostics platform with the legendary DBS operational culture and critical bioprocessing infrastructure. Both are high-quality healthcare equipment businesses with strong recurring revenue characteristics.

STE vs DHR compares two premium healthcare equipment companies — STERIS' specialized sterilization services dominance versus Danaher's diversified life sciences platform and operational excellence culture.

Live analysis · updated 6/20/2026

DHR holds the edge across 4 of 5 key metrics in this comparison. DHR has delivered stronger 1-year price return (-9.49% vs -14.54%), though STE trades at the lower forward P/E (17.14x vs 19.47x). On fundamentals, STE is growing revenue faster (7.30%), while DHR maintains the higher operating margin (22.94%) — a classic growth-versus-profitability split. Analyst consensus implies meaningfully more upside for DHR (+34.56%) than for STE (+23.75%).

Normalized 1Y performance
STE
DHR
Recent returns
STE
DHR
Analyst price targets & sentiment
STE · 9 analysts
STRONG BUYHOLDSTRONG SELL
Buy (2.2/5.0)
Price target range
analyst low$231.00
analyst high$280.00
analyst mean$256.86
current price$202.61
+23.8% upside to analyst mean
DHR · 23 analysts
STRONG BUYHOLDSTRONG SELL
Strong Buy (1.4/5.0)
Price target range
analyst low$210.00
analyst high$310.00
analyst mean$242.35
current price$177.17
+34.6% upside to analyst mean
Who should consider this stock?
STE may suit investors who:
  • Want focused exposure to hospital sterilization and surgical equipment services with high recurring contract revenue
  • Value STERIS' dominant market position and sticky customer relationships in infection prevention infrastructure
  • Prefer a simpler, narrower healthcare services business to Danaher's broader life science diversification
DHR may suit investors who:
  • Want diversified life science and diagnostics exposure across bioprocessing, analytical instruments, and environmental testing
  • Value the Danaher Business System as a durable operational discipline that consistently improves margins across acquired businesses
  • See Cytiva bioprocessing recovery as a catalyst after the biopharmaceutical inventory correction cycle completes
Performance & AI score
MetricSTEDHR
AI score49.950.3
AI rank#474#448
Latest close$202.61$177.17
1M return-5.51%+6.06%
6M return-19.49%-20.42%
1Y return-14.54%-9.49%
$10,000 invested — hypothetical growth (dividends reinvested)

How much would $10,000 be worth today if invested at the start of each period, with all dividends reinvested?

PeriodSTEDHR
1Y ago$8.58K (-14.2%)
started 2025-06-18
$9.11K (-8.9%)
started 2025-06-18
5Y ago$10.79K (+7.9%)
started 2021-06-21
$7.86K (-21.4%)
started 2021-06-21
10Y ago$36.26K (+262.6%)
started 2016-06-20
$61.46K (+514.6%)
started 2016-06-20

Hypothetical — past performance does not guarantee future results.

Valuation & upside potential
MetricSTEDHR
Market cap$20.23B$127.47B
Trailing P/E26.1734.84
Forward P/E17.1419.47
Price/Sales4.395.89
EV/Revenue3.695.71
Analyst target$256.86$242.35
Target upside+23.75%+34.56%
Growth, profitability & risk
MetricSTEDHR
Revenue growth7.30%3.70%
Earnings growth52.20%9.80%
EPS growth+52.20%+9.80%
FCF margin+14.11%+18.44%
Operating margin20.04%22.94%
Profit margin13.18%14.89%
ROIC proxy11.37%7.08%
Return on equity11.37%7.08%
Dividend yield1.21%0.89%
Beta0.920.83
Debt/equity29.0037.17
Current ratio2.091.87
Quick ratio1.341.40
Drawdown & downside risk

Lower drawdown and smaller single-period drops generally indicate a smoother ride, though they do not guarantee lower future risk.

1Y risk snapshot
STE max drawdown25.78%
DHR max drawdown33.11%
STE max wkly drop10.97%
DHR max wkly drop8.99%
5Y risk snapshot
STE max drawdown36.18%
DHR max drawdown44.20%
STE max wkly drop13.72%
DHR max wkly drop14.50%
10Y risk snapshot
STE max drawdown36.18%
DHR max drawdown44.20%
STE max wkly drop17.18%
DHR max wkly drop14.50%
Performance metrics by period
PeriodMetricSTEDHR
1YGrowth-14.23%-8.88%
CAGR-14.25%-8.89%
Sharpe ratio-0.71-0.35
Max drawdown25.78%33.11%
Max daily drop7.74%5.40%
Max wkly drop10.97%8.99%
5YGrowth+4.17%-22.65%
CAGR+0.82%-5.01%
Sharpe ratio-0.01-0.21
Max drawdown36.18%44.20%
Max daily drop10.89%9.73%
Max wkly drop13.72%14.50%
10YGrowth+228.79%+333.14%
CAGR+12.65%+15.80%
Sharpe ratio0.420.46
Max drawdown36.18%44.20%
Max daily drop11.59%9.73%
Max wkly drop17.18%14.50%
Business comparison
CategorySTEDHR
CompanySTERIS plcDanaher Corporation
SectorHealthcareHealthcare
IndustryMedical DevicesDiagnostics & Research
Core businessSTERIS provides sterilization, surgical equipment maintenance, and infection prevention products and services to hospitals, ambulatory surgery centers, pharmaceutical manufacturers, and life science companies, generating high-recurring-revenue service contracts.Danaher is a diversified life science and diagnostics company operating through biotechnology (Cytiva bioprocessing equipment), life science tools, environmental, and industrial technology segments, known for the Danaher Business System (DBS) operational excellence methodology.
Investor focusInvestors track STERIS' healthcare and applied sterilization service revenue growth, contract service revenue recurring proportion, and margin profile as a high-quality, recurring revenue healthcare services company.Investors track Danaher's core revenue growth excluding M&A and currency effects, bioprocessing segment demand from biopharmaceutical manufacturing, and free cash flow conversion as a measure of the DBS-driven operational discipline.
STE strengths
  • Dominant market position in hospital sterilization services creates sticky, recurring contract revenue with high customer retention
  • Applied sterilization technologies (AST) segment serves pharmaceutical and medical device manufacturers with outsourced sterilization services
  • Recurring service revenue from installed base of surgical equipment and sterilizers provides a predictable, capital-light growth model
DHR strengths
  • Danaher Business System (DBS) operational excellence culture consistently improves margins and returns across acquired businesses
  • Cytiva bioprocessing platform is critical infrastructure for biopharmaceutical drug manufacturing with long-term customer partnerships
  • Diversified portfolio across life sciences, diagnostics, and environmental water testing provides resilience across cycles
Risks to watch — STE
  • Hospital capital spending cycles affect new sterilizer equipment sales even as service revenue is more resilient
  • Surgical procedure volumes affect demand for surgical equipment and related consumables — any procedure volume slowdown impacts revenue
  • Competitive pressures from niche sterilization service providers in specific geographic or product markets
Risks to watch — DHR
  • Bioprocessing demand has been cyclical as biopharmaceutical customers worked through COVID-era inventory buildups
  • Fortive (FTV) and Envista (NVST) spinoffs have progressively simplified Danaher, but integration of Cytiva was transformative and took time
  • Valuation is typically premium, limiting upside in multiple-compression environments even with strong business fundamentals
Frequently asked questions
Hospital sterilization involves decontaminating surgical instruments, operating room equipment, and medical devices between uses — a regulatory requirement for every procedure. STERIS provides both the sterilization equipment and ongoing service contracts, creating predictable recurring revenue since hospitals must continuously sterilize regardless of economic conditions.
AI Prediction SignalNext 5 trading days
Members only
STE
+2.8%BUY
DHR
+1.1%HOLD

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