ABBV vs REGN Comparison: AI Score, Valuation, Performance and Upside
Compare AbbVie and Regeneron by post-Humira growth transition, Skyrizi and Rinvoq ramp, Dupixent label expansion, oncology pipeline, and which large-cap biotech offers better earnings visibility through 2030.
Use this AbbVie vs Regeneron comparison to evaluate the key differences across valuation, growth, profitability, and risk before making an investment decision.
ABBV holds the edge across 3 of 5 key metrics in this comparison. ABBV has delivered stronger 1-year price return (+35.91% vs +16.18%), though REGN has the better forward P/E setup (12.36x vs 15.63x for ABBV). On fundamentals, REGN is growing revenue faster (19.00%), while ABBV maintains the higher operating margin (32.16%) — a classic growth-versus-profitability split. Analyst consensus implies meaningfully more upside for REGN (+21.06%) than for ABBV (+4.75%).
| Metric | ABBV | REGN |
|---|---|---|
| AI score | 49.8 | 42.6 |
| AI rank | #521 | #904 |
| Latest close | $259.36 | $656.01 |
| 1M return | +10.42% | +5.23% |
| 6M return | +18.29% | -12.94% |
| 1Y return | +35.91% | +16.18% |
How much would $10,000 be worth today if invested at the start of each period, with all dividends reinvested?
| Period | ABBV | REGN |
|---|---|---|
| 1Y ago | $13.63K (+36.3%) started 2025-07-25 | $11.65K (+16.5%) started 2025-07-25 |
| 5Y ago | $29.71K (+197.1%) started 2021-07-26 | $11.4K (+14.0%) started 2021-07-26 |
| 10Y ago | $91.39K (+813.9%) started 2016-07-25 | $16.68K (+66.8%) started 2016-07-25 |
Hypothetical — past performance does not guarantee future results.
| Metric | ABBV | REGN |
|---|---|---|
| Market cap | $449.63B | $70.94B |
| Trailing P/E | 124.75 | 16.53 |
| Forward P/E | 15.63 | 12.36 |
| Price/Sales | 5.85 | 3.78 |
| EV/Revenue | 8.17 | 4.21 |
| Analyst target | $266.57 | $819.18 |
| Target upside | +4.75% | +21.06% |
| Metric | ABBV | REGN |
|---|---|---|
| Revenue growth | 12.40% | 19.00% |
| Earnings growth | -46.20% | -7.20% |
| EPS growth | -46.20% | -7.20% |
| FCF margin | +33.13% | +21.94% |
| Operating margin | 32.16% | 20.66% |
| Profit margin | 5.79% | 29.65% |
| ROIC proxy | 6225.00% | 14.55% |
| Return on equity | 6225.00% | 14.55% |
| Dividend yield | 2.72% | 0.56% |
| Beta | 0.28 | 0.24 |
| Debt/equity | 4789.60 | 8.61 |
| Current ratio | 0.80 | 3.56 |
| Quick ratio | 0.52 | 2.84 |
Lower drawdown and smaller single-period drops generally indicate a smoother ride, though they do not guarantee lower future risk.
| Period | Metric | ABBV | REGN |
|---|---|---|---|
| 1Y | Growth | +36.30% | +16.50% |
| CAGR | +36.43% | +16.55% | |
| Sharpe ratio | 1.16 | 0.50 | |
| Max drawdown | 19.23% | 26.05% | |
| Max daily drop | 5.20% | 9.82% | |
| Max wkly drop | 8.49% | 12.87% | |
| 5Y | Growth | +154.38% | +13.85% |
| CAGR | +20.55% | +2.63% | |
| Sharpe ratio | 0.73 | 0.09 | |
| Max drawdown | 21.92% | 59.69% | |
| Max daily drop | 12.57% | 19.01% | |
| Max wkly drop | 17.30% | 20.21% | |
| 10Y | Growth | +484.53% | +66.58% |
| CAGR | +19.31% | +5.24% | |
| Sharpe ratio | 0.64 | 0.18 | |
| Max drawdown | 45.09% | 59.69% | |
| Max daily drop | 16.25% | 19.01% | |
| Max wkly drop | 19.39% | 20.21% |
| Category | ABBV | REGN |
|---|---|---|
| Company | ABBV | REGN |
| Sector | Healthcare | Healthcare |
| Industry | Drug Manufacturers - General | Biotechnology |
| Core business | N/A | N/A |
| Investor focus | N/A | N/A |
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