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LLY
Eli Lilly and Company · Healthcare
$1,220.28
+3.25% this month
VERSUS
COMPARE
ABBV
AbbVie Inc. · Healthcare
$248.76
+0.31% this month
Scoreboard verdict
Across AI score, momentum, valuation, upside, operating margin
LLY
3
ABBV
2
Comparison scoreboard
LLY LEADS 3/5AI Score
LLY ✓79.7
ABBV 44.8
1Y Return
LLY ✓+90.84%
ABBV +25.23%
Fwd P/E
LLY 25.52
ABBV ✓15.09
Target Up.
LLY +9.01%
ABBV ✓+11.51%
Op. Margin
LLY ✓54.22%
ABBV 40.03%
Metrics last refreshed: 8/12/2026
Quick take
LLY vs ABBV: Eli Lilly vs AbbVie Stock Comparison: AI Score, Valuation, Performance and Upside
Eli Lilly is the GLP-1 growth juggernaut with the fastest-growing drug franchise in pharma history and massive obesity market expansion potential. AbbVie is a diversified pharma company navigating the Humira-to-Skyrizi/Rinvoq transition with a high dividend yield and broader therapeutic area exposure. Lilly has superior growth; AbbVie has better income and diversification.
Use this LLY vs ABBV comparison to evaluate two pharma investment approaches. Eli Lilly offers concentrated GLP-1/obesity growth at a premium valuation; AbbVie offers diversified pharma income with strong immunology growth at a more moderate valuation.
Live analysis · updated 8/12/2026
LLY holds the edge across 3 of 5 key metrics in this comparison. LLY has delivered stronger 1-year price return (+90.84% vs +25.23%), though ABBV has the better forward P/E setup (15.09x vs 25.52x for LLY). LLY leads on both revenue growth (47.70%) and operating margin (54.22%), suggesting a stronger fundamental setup on both dimensions. Analyst consensus implies similar upside for both: +9.01% for LLY and +11.51% for ABBV.
Normalized 1Y performance
LLY
ABBV
Recent returns
LLY
ABBV
Analyst price targets & sentiment
LLY · 27 analysts
STRONG BUYHOLDSTRONG SELL
Buy (1.8/5.0)
Price target range
analyst low$650.00
analyst mean$1,292.53
current price$1,220.28
+9.0% upside to analyst mean
ABBV · 27 analysts
STRONG BUYHOLDSTRONG SELL
Buy (2.0/5.0)
Price target range
analyst low$170.00
analyst mean$274.36
current price$248.76
+11.5% upside to analyst mean
Who should consider this stock?
LLY may suit investors who:
- Want exposure to the GLP-1/obesity megatrend through the market-leading tirzepatide franchise
- Believe the obesity drug market TAM is large enough to justify Eli Lilly's premium valuation
- Value Lilly's pipeline optionality in Alzheimer's, oncology, and next-generation oral GLP-1 formulations
- Are comfortable with a growth-stock valuation for a pharmaceutical company
ABBV may suit investors who:
- Prefer a diversified pharma company with exposure across immunology, aesthetics, neuroscience, and oncology
- Value AbbVie's high dividend yield and Dividend Aristocrat status for income-oriented portfolios
- Believe Skyrizi and Rinvoq can fully replace and exceed Humira revenue over the next several years
- Want pharma exposure at a more moderate valuation with better near-term income generation
Performance & AI score
| Metric | LLY | ABBV |
|---|---|---|
| AI score | 79.7 | 44.8 |
| AI rank | #17 | #626 |
| Latest close | $1,220.28 | $248.76 |
| 1M return | +3.25% | +0.31% |
| 6M return | +20.20% | +12.62% |
| 1Y return | +90.84% | +25.23% |
$10,000 invested — hypothetical growth (dividends reinvested)
How much would $10,000 be worth today if invested at the start of each period, with all dividends reinvested?
| Period | LLY | ABBV |
|---|---|---|
| 1Y ago | $18.48K (+84.8%) started 2025-08-13 | $12.35K (+23.5%) started 2025-08-13 |
| 5Y ago | $49.75K (+397.5%) started 2021-08-13 | $28.82K (+188.2%) started 2021-08-13 |
| 10Y ago | $206.71K (+1967.1%) started 2016-08-15 | $83.66K (+736.6%) started 2016-08-15 |
Hypothetical — past performance does not guarantee future results.
Valuation & upside potential
| Metric | LLY | ABBV |
|---|---|---|
| Market cap | $1.06T | $434.78B |
| Trailing P/E | 39.84 | 69.50 |
| Forward P/E | 25.52 | 15.09 |
| Price/Sales | 14.10 | 5.85 |
| EV/Revenue | 13.84 | 7.75 |
| Analyst target | $1,292.53 | $274.36 |
| Target upside | +9.01% | +11.51% |
Growth, profitability & risk
| Metric | LLY | ABBV |
|---|---|---|
| Revenue growth | 47.70% | 10.20% |
| Earnings growth | 26.20% | 290.40% |
| EPS growth | +26.20% | +290.40% |
| FCF margin | +13.89% | +26.20% |
| Operating margin | 54.22% | 40.03% |
| Profit margin | 33.53% | 9.80% |
| ROIC proxy | 102.29% | 6225.00% |
| Return on equity | 102.29% | 6225.00% |
| Dividend yield | 0.58% | 2.81% |
| Beta | 0.51 | 0.28 |
| Debt/equity | 162.07 | 4789.60 |
| Current ratio | 1.35 | 0.81 |
| Quick ratio | 0.68 | 0.49 |
Drawdown & downside risk
Lower drawdown and smaller single-period drops generally indicate a smoother ride, though they do not guarantee lower future risk.
1Y risk snapshot
LLY max drawdown23.31%
ABBV max drawdown19.23%
LLY max wkly drop8.60%
ABBV max wkly drop8.49%
5Y risk snapshot
LLY max drawdown34.48%
ABBV max drawdown21.92%
LLY max wkly drop17.93%
ABBV max wkly drop17.30%
10Y risk snapshot
LLY max drawdown34.48%
ABBV max drawdown45.09%
LLY max wkly drop17.93%
ABBV max wkly drop19.39%
Performance metrics by period
| Period | Metric | LLY | ABBV |
|---|---|---|---|
| 1Y | Growth | +84.75% | +23.47% |
| CAGR | +85.11% | +23.55% | |
| Sharpe ratio | 1.79 | 0.77 | |
| Max drawdown | 23.31% | 19.23% | |
| Max daily drop | 7.79% | 5.20% | |
| Max wkly drop | 8.60% | 8.49% | |
| 5Y | Growth | +379.22% | +146.73% |
| CAGR | +36.82% | +19.80% | |
| Sharpe ratio | 0.99 | 0.70 | |
| Max drawdown | 34.48% | 21.92% | |
| Max daily drop | 14.14% | 12.57% | |
| Max wkly drop | 17.93% | 17.30% | |
| 10Y | Growth | +1662.99% | +435.10% |
| CAGR | +33.27% | +18.28% | |
| Sharpe ratio | 0.95 | 0.61 | |
| Max drawdown | 34.48% | 45.09% | |
| Max daily drop | 14.14% | 16.25% | |
| Max wkly drop | 17.93% | 19.39% |
Business comparison
| Category | LLY | ABBV |
|---|---|---|
| Company | Eli Lilly and Company | AbbVie Inc. |
| Sector | Healthcare | Healthcare |
| Industry | Drug Manufacturers - General | Drug Manufacturers - General |
| Core business | Global pharmaceutical company leading the GLP-1 revolution with Mounjaro (tirzepatide) for diabetes and Zepbound for obesity. Also developing treatments in Alzheimer's, oncology, and immunology. | Global biopharmaceutical company with leading positions in immunology (Skyrizi, Rinvoq), aesthetics (Botox, Juvederm), neuroscience, oncology, and eye care. Navigating the Humira biosimilar transition. |
| Investor focus | Mounjaro/Zepbound prescription growth, manufacturing capacity expansion, obesity market penetration, Alzheimer's drug (donanemab) commercial launch, and pipeline depth. | Skyrizi and Rinvoq growth trajectory post-Humira, aesthetics recovery, neuroscience pipeline, dividend sustainability, and revenue diversification beyond immunology. |
LLY strengths
- Market-leading GLP-1 franchise — Mounjaro and Zepbound are the fastest-growing drug brands in pharma history
- Obesity represents a massive TAM expansion — tens of millions of potential patients beyond the diabetes population
- Strong pipeline with donanemab (Alzheimer's), oncology assets, and next-generation oral GLP-1 formulations
ABBV strengths
- Skyrizi and Rinvoq are successfully replacing Humira revenue with combined peak sales potentially exceeding Humira's peak
- Diversified revenue across immunology, aesthetics (Allergan), neuroscience, and oncology provides stability
- Strong dividend with high yield — AbbVie is a Dividend Aristocrat with a commitment to growing its payout
Risks to watch — LLY
- Premium valuation (highest P/E among large-cap pharma) requires sustained GLP-1 demand and supply execution
- Manufacturing capacity constraints for tirzepatide — scaling production to meet demand is a multi-year challenge
- GLP-1 competition from Novo Nordisk (semaglutide) and emerging oral GLP-1 players could pressure market share
Risks to watch — ABBV
- Humira biosimilar erosion continues — Skyrizi and Rinvoq must grow fast enough to offset the decline
- Aesthetics market (Botox, Juvederm) has been softer than expected due to consumer spending headwinds
- Patent cliffs on key drugs create ongoing need for pipeline replenishment through R&D and M&A
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